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It spans from traditional imaging findings to more recent and intricate diagnoses, offering insights and highlighting advancements in neuroimaging technology that can. They may occur at any age and can manifest with a broad range and severity of symptoms. This review outlines the key genetic and clinical aspects of primary mitochondrial disorders pertinent to imaging characteristics and covers both conventional imaging findings.

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Investigation of the clinical, imaging, and in vivo mr spectroscopy (mrs) characteristics of disorders of mitochondrial function. Primary mitochondrial disorders are a clinically and radiologically heterogeneous group of conditions caused by pathologic variants in mitochondrial dna (mtdna) or nuclear. The complexity of white matter microarchitecture in mitochondrial disorders underscores the importance of dti as a tool;

As mitochondria, which have their own dna,.

Clinical, imaging (five ct and 20 mr examinations), and. Leigh syndrome, also known as subacute necrotizing encephalomyelopathy (snem), is a mitochondrial disorder characterized by progressive neurodegeneration,. Primary mitochondrial disorders (pmds) constitute the most common cause of inborn errors of metabolism in children, and they frequently affect the central nervous system. However, the findings need to be interpreted in the context of.

Primary mitochondrial disorders are clinically (and radiologically) heterogeneous.